Article Text

other Versions

PDF
Prematurity and programming of cardiovascular disease risk: a future challenge for public health?
  1. Elizabeth Bayman1,
  2. Amanda J Drake2,
  3. Chinthika Piyasena2
  1. 1Royal Hospital for Sick Children, Edinburgh, UK
  2. 2Endocrinology Unit, University/British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh, UK
  1. Correspondence to Dr Amanda J Drake, Endocrinology Unit, University/BHF Centre for Cardiovascular Science, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh EH16 4TJ, UK; mandy.drake{at}ed.ac.uk

Abstract

There is substantial epidemiological evidence linking low birth weight with adult cardiometabolic disease risk factors. This has led to the concept of ‘early life programming’ or the ‘developmental origins of disease’ which proposes that exposure to adverse conditions during critical stages of early development results in compensatory mechanisms predicted to aid survival. There is growing evidence that preterm infants, many of whom are of low birth weight, are also at increased risk of adult cardiometabolic disease. In this article, we provide a broad overview of the evidence linking preterm birth and cardiovascular disease risk and discuss potential consequences for public health.

  • Metabolic
  • Neonatology
  • Obesity
  • Vascular Disease

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.