Article Text

other Versions

PDF
Letter
Prospective controlled study to evaluate cryocontact therapy for infantile haemangioma in preterm infants
  1. Rangmar Goelz1,
  2. Monika Moll1,
  3. Christoph Meisner2,
  4. Martin Röcken3,
  5. Christian F Poets1,
  6. Matthias C Moehrle3
  1. 1Department of Neonatology, University Childrens's Hospital, Tuebingen, Germany
  2. 2Institute of Medical Biometry, Tuebingen, Germany
  3. 3University Hospital of Dermatology, Tuebingen, Germany
  1. Correspondence to Dr Rangmar Goelz, Department of of Neonatology, University Childrens Hospital, Calwerstrasse 7, Tuebingen D-72076, Germany; Rangmar.Goelz{at}med.uni-tuebingen.de

Statistics from Altmetric.com

Despite the high prevalence of infantile haemangioma (IH) of preterm infants, methods for treating it have not yet been evaluated in controlled trials.1 Therefore, we conducted a prospective controlled study, comparing nitrogen-cooled cryocontact therapy (NCCT,−196°C) for early treatment of IH in preterm infants with no treatment.

From 1 August 2004 to 31 December 2008, we allocated IH of infants ≤34 weeks gestational age with at least two IH into either a cryocontact or a control group, thus using intraindividual controls to exclude interpersonal differences potentially affecting growth. If IH appeared simultaneously, they were numbered from head to foot; even numbers were treated, odd numbers served as controls. In sequentially erupting IH, always the second one …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.