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Ureaplasma species: role in neonatal morbidities and outcomes
  1. Rose Marie Viscardi
  1. Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, USA
  1. Correspondence to Dr Rose M Viscardi, Department of Pediatrics, University of Maryland School of Medicine, 110 S. Paca Street, 8th floor, Baltimore, MD 21201, USA; rviscard{at}umaryland.edu

Abstract

The genital mycoplasma species, Ureaplasma parvum and Ureaplasma urealyticum are the most common organisms isolated from infected amniotic fluid and placentas, and they contribute to adverse pregnancy outcomes including preterm birth and neonatal morbidities. In our institution, almost half of the preterm infants of less than 32 weeks gestation are Ureaplasma-positive in one or more compartment (respiratory, blood and/or cerebrospinal fluid), indicating that these organisms are the most common pathogens affecting this population. This review will focus on the compelling epidemiological and experimental evidence linking perinatal Ureaplasma species exposure to important morbidities of prematurity, such as bronchopulmonary dysplasia, intraventricular haemorrhage and necrotising enterocolitis.

  • Neonatology
  • Ureaplasma Parvum
  • Ureaplasma Urealyticum
  • Bronchopulmonary Dysplasia
  • Intraventricular Hemorrhage

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