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It was with great interest that we read the article by Choong et al, ‘Remifentanil for endotracheal intubation in neonates: a randomised controlled trial’.1 First of all, we would like to congratulate the authors on their randomised controlled trial (RCT). However, there are some issues that should be raised.
The premedication protocol for endotracheal intubation in this study includes many classes of drugs besides opioids that might interfere with physiological responses. For instance, the administration of …
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