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Neonatal Outcomes of Macrosomic Births in Diabetic and Non-diabetic Women
  1. Srikant Das (drsrikantdas{at}hotmail.com)
  1. Emory University, United States
    1. Matilde Irigoyen (irigoyem{at}einstein.edu)
    1. Albert Einstein Medical Center, United States
      1. Agnes Salvador (salvadoa{at}einstein.edu)
      1. Albert Einstein Medical Center, United States
        1. Mary Beth Patterson (mpatterson{at}labiomed.org)
        1. UCLA Children's Hospital of Los Angeles, United States
          1. David L Schutzman (schutzmand{at}einstein.edu)
          1. Albert Einstein Medical Center, United States

            Abstract

            Objective: To compare the neonatal outcomes and birth injuries of macrosomic infants born to diabetic mothers (IDM) and non-diabetic (non-IDM) mothers.

            Study design: This is a retrospective survey of all live born, singleton neonates with a birth weight of ≥ 4000 grams, delivered at the Albert Einstein Medical Center, Philadelphia during a three-year period, 2003 through 2005. 305 infants of the 7158 deliveries during this period met entry criteria. Data was analyzed using Chi square and Fisher exact test. Logistic regression analysis was also performed.

            Result: Compared to IDMs, non-IDMs were born later (40 vs. 38 weeks) and were more likely to be delivered vaginally (70% vs. 34%). Half of the non-IDMs (49.6%) suffered at least one morbidity compared to 73.2% of the IDMs. Non-IDMs had a higher incidence of birth injury than IDMs (8% vs. 2.4%). Logistic regression showed an increased risk of poor outcome with weight >4499 gm. and vaginal delivery.

            Conclusion: All macrosomic infants represent a high-risk group, regardless of maternal diabetes status.

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