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Severe retinopathy of prematurity in infants <30 weeks' gestation in New South Wales (NSW) and the Australian Capital Territory (ACT) from 1992-2002
  1. David A Todd (david.todd{at}act.gov.au)
  1. Neonatal Intensive Care Unit (NICU), The Canberra Hospital, Woden, Australia
    1. Audrey Wright
    1. NICU, Westmead Hospital, Westmead, NSW, Australia
      1. Jeremy Smith
      1. Department of Ophthalmology, Westmead Hospital, Westmead, NSW, Australia
        1. The NICUS Group
        1. The Neonatal Intensive Care Units' (NICUS) group, Australia

          Abstract

          Background: Retinopathy of prematurity (ROP) significantly increased in New South Wales (NSW) from 1986 to 1994, but more recent data suggests that there has now been a decrease.

          Objective: To study the incidence and treatment of severe ROP (Stage ≥ 3) in NSW and the Australian Capital Territory (ACT) from 1992 to 2002.

          Methods: Data collected prospectively from the Neonatal Intensive Care Units' (NICUS) Data Collection over an 11 year period in infants <30 weeks' gestation were divided into 4 epochs and analysed retrospectively. The incidence and treatment of severe ROP were compared for gestational ages ≤24 weeks', 25-26 weeks' and 27- 29 weeks' gestation over the 4 epochs.

          Results: In infants ≤24 weeks' gestation the incidence of severe ROP and those treated increased significantly (Stage ≥ 3; 17 [41.5%] to 41 [53.9%], p=0.052 and treated: 8 [19.5%] to 25 [32.9%], p<0.05 [1st and 4th epoch]). In infants 25-26 weeks' gestation the incidence of severe ROP decreased significantly while there was a non-significant increase in those treated (Stage ≥ 3; 55 [26.2%] to 46 [19.3%], p<0.05 and treated: 19 [9.0%] to 32 [13.4%], p=ns). In infants 27-29 weeks' gestation, there was no significant change in the incidence of severe ROP or those treated (Stage & [ge] 3; 30 [4.1%] to 17 [2.4%], p=ns and treated: 14 [1.9%] to 8 [1.1%], p=ns).

          Conclusion: In infants ≤24 weeks' gestation has there been a significant increase in severe ROP, while treatment for severe ROP increased in infants <27 weeks' gestation.

          • cryo-therapy and laser therapy
          • preterm infants
          • retinopathy of prematurity

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