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Arch Dis Child Fetal Neonatal Ed 99:F240-F244 doi:10.1136/archdischild-2013-303762
  • Review

Management of neonatal herpes simplex virus infection and exposure

  1. David W Kimberlin
  1. Division of Pediatric Infectious Diseases, The University of Alabama at Birmingham, Birmingham, Alabama, USA
  1. Correspondence to Dr David W Kimberlin, Division of Pediatric Infectious Diseases, The University of Alabama at Birmingham, 1600 Seventh Avenue South, CHB 303, Birmingham, AL 35233, USA; dkimberlin{at}peds.uab.edu
  • Received 29 August 2013
  • Revised 23 December 2013
  • Accepted 30 December 2013
  • Published Online First 3 March 2014

Abstract

Neonatal herpes simplex virus (HSV) infections are rare but are associated with significant morbidity and mortality. Advances in diagnostic modalities to identify these infants, as well as the development of safe and effective antiviral therapy, have revolutionised the management of affected infants. This review will summarise the epidemiology of neonatal HSV infections and discuss the management of infants with HSV exposure and infection.

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