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PP.55 Screening Women for Asymptomatic Bacteriuria in Early Pregnancy May Reduce the Risk of Low Birth Weight
  1. HE Browne1,
  2. EA Bonney1,
  3. LA McDowell2,
  4. J Young2,
  5. NAB Simpson1
  1. 1Division of Clinical Sciences, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, UK
  2. 2School of Medicine, University of Leeds, Leeds, UK

Abstract

Introduction Anatomical changes in pregnancy predispose women to asymptomatic bacteriuria (ASB). Current NICE guidance in the UK advises that a mid-stream urine (MSU) sample should be offered in early pregnancy to screen for and treat ASB.

Aims To investigate how many women currently have an MSU in early pregnancy (<18 weeks gestation) in an inner-city maternity unit; to evaluate whether current screening practise affects pregnancy outcome.

Methods This was a retrospective cohort study which examined notes of all delivered women who gave birth within a three-week period. Appropriate parametric and non-parametric tests were used to determine intergroup differences.

Results 243 women delivered during this period. Although all had been booked before 18 weeks gestation, only 9% (n = 22) had been screened for ASB. Of the unscreened population, 18% (n = 40) subsequently developed a UTI in pregnancy, and these were more likely to deliver a LBW baby (18% <2500 g; OR 2.9, 95th CI 1.1–7.9). The screened population had rates of LBW (4%) which were the same as the unaffected cohort within the unscreened population (6%).

Conclusion These data suggest that a policy of not screening for ASB may increase the chance of LBW babies being born. Although other confounding variables were not controlled for in this study, the evidence would suggest a policy of screening for ASB remains a reasonable option in pregnancy. (supported by Cerebra).

  • Asymptomatic bacteriuria
  • pyelonephritis
  • preterm labour
  • low birth-weight

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