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PP.01 Perinatal Outcome of IUGR Pregnancies with Normal and Abnormal Doppler Studies – The Prospective Multicentre Porto Trial
  1. J Unterscheider,
  2. S Daly,
  3. MP Geary,
  4. MM Kennelly,
  5. FM McAuliffe,
  6. K O’Donoghue,
  7. A Hunter,
  8. JJ Morrison,
  9. G Burke,
  10. P Dicker,
  11. EC Tully,
  12. FD Malone
  1. Perinatal Ireland Research Consortium, Dublin, Ireland

Abstract

Objective The objective of this analysis, as part of the multicentre prospective PORTO Trial, was to describe and compare perinatal outcomes of IUGR pregnancies with normal and abnormal umbilical artery (UA) Doppler studies.

Study design The PORTO Trial recruited over 1,100 consecutive ultrasound-dated singleton IUGR pregnancies, defined as EFW < 10th centile. All fetuses underwent serial sonographic assessment until birth. Perinatal outcomes were documented for all participants.

Results Of the 1,118 recruited patients, 606 (54%) had normal UA Doppler studies and 512 (46%) had abnormal UA Dopplers, defined as UA PI > 95th centile or AREDF. The group with abnormal UA Doppler was delivered earlier and more commonly by CS, had more admissions to NICU and adverse perinatal outcomes (Table 1). The 4 mortalities with normal Doppler all had EFW < 3rd centile.

Abstract PP.01 Table 1

Comparison of groups with normal and abnormal UA Doppler

Conclusion IUGR fetuses with normal UA Doppler studies have better perinatal outcomes than those with abnormal UA Doppler, however adverse perinatal outcome can occur with normal UA in more severe IUGR cases (EFW < 3rd centile).

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