Arch Dis Child Fetal Neonatal Ed 98:F182 doi:10.1136/archdischild-2012-302230
  • PostScript
  • Letters

Newborn screening of congenital cytomegalovirus infection using saliva can be influenced by breast feeding

  1. Hiroshi Azuma1
  1. 1Department of Paediatrics, Asahikawa Medical University, Asahikawa, Japan
  2. 2Department of Virology I, National Institute of Infectious Diseases, Tokyo, Japan
  3. 3Department of Paediatrics, Nagasaki University, Nagasaki, Japan
  1. Correspondence to Dr Shin Koyano, Department of Paediatrics, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa 078-8510, Japan; koyano5p{at}
  • Received 20 April 2012
  • Revised 20 April 2012
  • Accepted 18 June 2012
  • Published Online First 8 August 2012

Congenital cytomegalovirus (cCMV) infection occurs in 0.2–2% of all births in developed countries and causes developmental abnormalities.1 In addition to patients symptomatic at birth, asymptomatic newborns can develop late-onset sequelae, including sensorineural hearing loss and developmental delay. As the early identification of congenitally infected newborns may allow early intervention and antiviral treatment options, it is important to establish newborn cCMV screening programmes.

Since newborn screening assays using dried blood spots for cCMV infection were …

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