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Preterm neonates experience a large number of painful procedures during their stay in the neonatal intensive care units (NICUs) and these procedures are often not accompanied by satisfactory analgesia.1 2 Peripherally inserted central catheter (PICC) insertion is a painful intervention employed recurrently to provide a secure venous access.3,–,7
The aim of this study was to determine whether 25% oral glucose or EMLA cream was a better strategy for controlling pain in preterm neonates undergoing PICC insertion.
A randomised, triple-masked controlled trial was conducted at two tertiary NICUs in the city of Belo Horizonte, Brazil. Participants included 30 preterm neonates (≥28 and <37 weeks of gestational age) during the first week of life with a clinical indication …
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