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Thresholds for antibiotic resistance at which we change empirical treatment choices
  1. Michael Millar
  1. Correspondence to Dr Michael Millar, Department of Infection, Barts and The London NHS Trust, Pathology and Pharmacy Building, 3rd Floor, 80 Newark St, Whitechapel, London E1 2ES, UK; m.r.millar{at}qmul.ac.uk

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In a recent paper published in this journal,1 the laboratory results from 1516 infants with laboratory-confirmed early neonatal infections were reported for the 27-month period up to March 2008 (approximately 674 cases per year). Six per cent of laboratory isolates from infants younger than 48 h were reported as resistant to empirical treatment with penicillin and gentamicin. This means that 40 infants (6% of 674 infants per year) would have received antibiotic treatment to …

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