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Sildenafil use in congenital diaphragmatic hernia
  1. L Hunter1,
  2. T Richens2,
  3. C Davis1,
  4. G Walker1,
  5. J H Simpson1
  1. 1
    Neonatal Intensive Care Unit, Royal Hospital for Sick Children, Glasgow, UK
  2. 2
    Department of Cardiology, Royal Hospital for Sick Children, Glasgow, UK
  1. Correspondence to Lindsey Hunter, Flat 3/2, 15 Malta Terrace, Glasgow G5 OTN, UK; lhunter{at}doctors.org.uk

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The postnatal management of severe congenital diaphragmatic hernia (CDH) remains challenging with few robust evidence-based interventions but many therapies based on case reports or small case series. A good example of this is sildenafil, a phosphodiesterase inhibitor, which is increasingly used in the management of pulmonary hypertension associated with CDH.1 2

We retrospectively audited sildenafil use in all infants with CDH managed in the co-located Queen Mother’s Hospital and the Royal Hospital for Sick Children, …

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