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Severe bilateral intracranial haemorrhage due to alloimmune thrombozytopenia in a premature infant
  1. M Wilke1,2,3,
  2. I Müller-Hansen2,
  3. D Wernet4,
  4. T Nägele5,
  5. C F Poets2
  1. 1
    Department of Pediatric Neurology and Developmental Medicine, University of Tübingen, Germany
  2. 2
    Department of Neonatology, University Children’s Hospital, University of Tübingen, Germany
  3. 3
    Section for Experimental MR of the CNS, Department of Neuroradiology, University of Tübingen, Germany
  4. 4
    Department of Transfusion Medicine, University of Tübingen, Germany
  5. 5
    Department of Neuroradiology, University of Tübingen, Germany
  1. Correspondence to Marko Wilke, Department of Pediatric Neurology and Developmental Medicine, University Children’s Hospital, Hoppe-Seyler-Str. 1, 72076 Tübingen, Germany; Marko.Wilke{at}med.uni-tuebingen.de

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A boy weighing 1310 g was born by caesarean section at 30 2/7 weeks’ gestation due to premature contractions. Fetal ultrasound 24 hours prior to delivery was normal. Postnatal cardio-pulmonary adaptation was poor and petechiae were noted. Thrombocytopenia (7.000/μl) and anaemia (7 g/dl) were present requiring transfusion of thrombocytes and packed red blood cells. Following detection of intracranial haemorrhage by ultrasound (fig 1), cranial MRI was done at 8 h of age on a 1.5T MR scanner (Philips, …

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