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Postnatal glucocorticoids in preterm neonates: use in French neonatal centres in 2006
  1. E Autret-Leca1,2,
  2. S Bauer3,
  3. C Alberti4,
  4. A P Jonville-Béra1,
  5. Y Aujard5,
  6. L Bensouda-Grimaldi1,2,
  7. O Baud5
  1. 1
    CHRU de Tours, Hôpital Bretonneau, Service de Pharmacologie Clinique, Centre Régional de Pharmacovigilance et d’Information sur le médicament, Tours, France
  2. 2
    Université François Rabelais Tours, Service de Pharmacologie Clinique, Centre Régional de Pharmacovigilance et d’Information sur le médicament, Tours, France
  3. 3
    CHRU de Tours, Hôpital Bretonneau, Service de Pharmacologie Clinique, Centre Régional de Pharmacovigilance et d’Information sur le médicament, Tours, France
  4. 4
    Assistance Publique – Hôpitaux de Paris, Hôpital Robert Debré, Unité d’Epidémiologie Clinique, Paris, France
  5. 5
    Assistance Publique – Hôpitaux de Paris, Hôpital Robert Debré, Service de Réanimation et Pédiatrie Néonatales, Paris, France
  1. Professor E Autret-Leca, Service de Pharmacologie—CHRU de Tours—2 boulevard Tonnellé, 37044 Tours cedex 9, France; autret-leca{at}med.univ-tours.fr

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In 1999, 80% of French neonatal centres used corticosteroids, mainly betamethasone, to prevent or to treat bronchopulmonary dysplasia (BPD).1 As many data suggested a low benefit/risk ratio, an updated assessment of this use was necessary.25

Methods

Questionnaires addressing the use of and indications for corticosteroids were sent to all French neonatal centres.

Results

The study was performed over five months (July–November 2006). Questionnaires were sent to 202 centres, of which 186 (92%) centres completed them. Of these 186 centres, 147 (79%) units had a standard protocol for corticosteroids use, …

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