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Arch Dis Child Fetal Neonatal Ed 2008;93:F251
  • Fantoms

Fantoms

  1. Martin Ward Platt, Deputy Editor

      TARGETING THE DUCT

      Echoing the duct, and measuring parameters such as left atrial size, will always be the mainstay of assessment for babies where there is clinical suspicion of a significant patent duct. Routine anti-duct treatment of all babies under a certain birth weight or gestation, though briefly fashionable, has faded out through lack of convincing evidence. The new and interesting question is whether to actively seek out those babies with a significant duct earlier than symptoms develop, and treat it if it fulfils criteria for being actually or potentially haemodynamically significant. Exactly what is meant by “significant” is a matter for debate, but Farombi-Oghuvbu et al have made a contribution by demonstrating that N-terminal pro-B-type natriuretic peptide concentrations may be a useful marker for “significance”. Exactly how such measurements may be used, and how they may add value to, or substitute for echocardiography, will need further …

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