Renovascular hypertension commencing during fetal life
- 1Departments of Paediatric Nephrology, Royal Victoria Infirmary, Newcastle, UK
- 2Departments of Pathology, Royal Victoria Infirmary, Newcastle, UK
- Correspondence to:
Malcolm G Coulthard
Departments of Paediatric Nephrology, Royal Victoria Infirmary, Newcastle, NE1 4LP;
- Accepted 24 July 2006
- Published Online First 21 September 2006
We report three infants with severe, early hypertension due to unilateral renovascular disease, whose cardiovascular changes, or polycythaemia, or both, indicated they had been affected as fetuses. All underwent unilateral nephrectomy, and had a similar histology, with patchy areas having relatively normal glomeruli but immature proximal tubules. This pattern may be a marker for renovascular disease in fetal life.
Competing interests: None declared.