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Iodine deficiency associated with parenteral nutrition in extreme preterm infants
  1. M Ibrahim1,
  2. G Morreale de Escobar2,
  3. T J Visser3,
  4. S Durán2,
  5. H van Toor3,
  6. J Strachan4,
  7. F L R Williams5,
  8. R Hume1
  1. 1Tayside Institute of Child Health, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK
  2. 2Departmento de Endocrinologia, Instituto de Investigaciones Biomedicas “Alberto Sols” Arturo Duperier 4, Spanish Research Council and Autonomous University of Madrid, Madrid 28029, Spain
  3. 3Department of Internal Medicine III, Erasmus University, University Hospital Dijkzigt, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
  4. 4Department of Biochemical Medicine, Ninewells Hospital and Medical School
  5. 5Department of Epidemiology and Public Health, University of Dundee, Ninewells Hospital and Medical School
  1. Correspondence to:
    Professor Hume, Tayside Institute of Child Health, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland UK;
    r.hume{at}dundee.ac.uk

Abstract

Infants are in negative iodine balance on current standard regimens of total parenteral nutrition, with a mean iodine intake of 3 μg/kg/day (150 ml/kg/day). The recommended enteral intake of iodine for preterm infants is 30 μg/kg/day. Gastrointestinal absorption of iodine is high, suggesting that parenteral intakes should approach enteral recommendations.

  • preterm
  • iodine
  • thyroid
  • parenteral nutrition

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