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Endothelin 1 concentrations in infants with meconium stained amniotic fluid
  1. S Yigit1,
  2. G Tekinalp1,
  3. O Oran1,
  4. M Yurdakok1,
  5. D Aliefendioglu2,
  6. A Gurgey3
  1. 1Hacettepe University Hospital, Department of Pediatrics, Division of Neonatology
  2. 2Social Security Hospital, Ankara
  3. 3Hacettepe University Hospital, Department of Pediatrics, Division of Haematology
  1. Correspondence to:
    Dr S Yigit, Ziraat Mühendisleri Sitesi 3/21 Çankaya 06550, Ankara, Turkey;
    Suleyigit{at}turk.net

Abstract

Plasma endothelin 1 concentrations were determined in infants with meconium stained amniotic fluid. Plasma endothelin 1 concentration in the study group (5.23 pg/ml) was statistically higher than that in the control group (1.12 pg/ml). Cord blood pH and base excess values were significantly lower in infants with meconium stained amniotic fluid when compared with the control group. There was no correlation between endothelin 1 concentrations and pH or base excess values. Results suggest that meconium passage is not a physiological event, even if meconium stained infants appear to be clinically healthy.

  • meconium stained amniotic fluid
  • endothelin-1, meconium aspiration syndrome
  • newborn
  • MAS, meconium aspiration syndrome
  • MSAF, meconium stained amniotic fluid

https://doi.org/10.1136/fn.87.3.F212

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