Editor—We are concerned that intravenous steroids are increasingly being used for the treatment of early neonatal hypotension without proper evaluation. We recently treated three newborn premature infants who had received a six day reducing course of intravenous hydrocortisone (starting at 12.5 mg/kg/day in divided doses) from day 1 of age for the treatment of hypotension. They were otherwise stable, apart from one infant who had a patent ductus arteriosus. All developed severe systemic …