Article Text


Granulocyte colony stimulating factor treatment for neonatal neutropenia.
  1. A. R. Russell,
  2. E. G. Davies,
  3. S. E. Ball,
  4. E. Gordon-Smith
  1. Department of Child Health, St George's Hospital Medical School, London.


    In a pilot study recombinant human granulocyte colony-stimulating factor (rhG-CSF) was administered to 12 neutropenic preterm infants to determine if neonatal neutropenia is secondary to decreased endogenous G-CSF production. Respiratory variables were monitored because of the possible link between inflammatory cells and hyaline membrane disease. All infants showed increased neutrophil counts. The only possible side effect observed was an exacerbation of thrombocytopenia.

    Statistics from

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.