Article Text

PDF
Sustained lung inflation at birth: what do we know, and what do we need to know?
  1. Karen E McCall1,2,
  2. Peter G Davis1,3,4,
  3. Louise S Owen1,3,4,
  4. David G Tingay1,4,5,6
  1. 1Newborn Research, Murdoch Children's Research Institute, Melbourne, Australia
  2. 2School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
  3. 3Department of Obstetrics, University of Melbourne, Melbourne, Australia
  4. 4Neonatal Research, Royal Women's Hospital, Melbourne, Australia
  5. 5Department of Neonatology, Royal Children's Hospital, Melbourne, Australia
  6. 6Department of Paediatrics, University of Melbourne, Melbourne, Australia
  1. Correspondence to Dr Karen E McCall, Neonatal Research, Murdoch Children's Research Institute, 50 Flemington Road, Parkville, VIC 3052, Australia; Karen.McCall{at}rch.org.au

Abstract

A sustained inflation has been advocated as a potential method of augmenting lung aeration at birth. Clinical trials have suggested that a sustained inflation may lead to a reduced need for intubation and ventilation in the first few days of life, without cardiovascular compromise or increased lung injury. Despite this, a sustained inflation is not currently a standard of practice, mainly due to a lack of clarity regarding the optimal delivery method. Animal trials have sought to refine delivery techniques. This review will outline current recommendations regarding a sustained inflation, discuss potential strategies for its optimal delivery and suggest priorities for future research.

  • Resuscitation
  • Neonatology
  • Respiratory

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • Fantoms
    Ben J Stenson