Arch. Dis. Child. Fetal Neonatal Ed.. Published Online First: 20 October 2005. doi:10.1136/adc.2005.079079
Original articles |
Echocardiographic assessment of early circulatory status in preterm infants with suspected intrauterine infection
1 Kakogawa Municipal Hospital, Japan
* To whom correspondence should be addressed. E-mail: m-m-mura{at}ya2.so-net.ne.jp.
Accepted 19 September 2005
Abstract
Objective:To assess early circulatory status in very low birth weight (VLBW) infants with suspected intrauterine infections.
Patients:13 VLBW infants who were diagnosed as infants with prenatal infections because of an elevation of serum immunoglobulin M (IgM) at birth (infectious group), and 39 gestational age-birth weight-matched infants (control group).
Methods:Echocardiographic assessments were performed consecutively from birth to days 28 in all VLBW infants. Left ventricular output (LVO) and left ventricular stroke volume (LVSV) were measured using Doppler echocardiography. Pulsed-Doppler assessment of pulmonary artery pressure (PAP) was performed by the corrected ratio of the pulmonary artery acceleration time to the right ventricular ejection time (AT:RVET (c)). Evaluation of blood flow in the superior mesenteric artery (SMA)was also performed by Doppler ultrasound.
Results:Both mean values of LVO and LVSV in infectious group were significantly higher than those in control group at 12h(LVO; 188 vs 154 ml/kg/min) and 72h of life (LVO; 216 vs 173ml/kg/min). Pulsed-Doppler assessment of PAP showed that mean values of AT:RVET(c) in infectious group were significantly lower than those in control group at 48h, 96h, on days 14, and days 28. In the analysis of SMA flow velocities, both peak systolic velocities (Vs) and time-averaged velocities (TAV) decreased significantly in infectious group compared to those in control group at 24h, 36h, 96h, and on days 28.
Conclusions:VLBW infants with suspected prenatal infections showed unique status of circulation, namely high cardiac output, latency of high PAP, and low organ flow.
Keywords: cardiac output, chronic lung disease, organ blood flow, prenatal infection, pulmonary hypertension
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- Re: Echocardiographic assessment of early circulatory status in preterm infants with suspected intra
- Dr Tom Dawson, et al.
- Fetal Neonatal Ed. Online, 14 Mar 2006 [Full text]
- Preterm Left Ventricular output is not systemic blood flow.
- Nick Evans
- Fetal Neonatal Ed. Online, 29 Mar 2006 [Full text]
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