ABSTRACTS
Poster presentations - Pregnancy outcome
| The first 150 words of the full text of this article appear below. |
DETERMINANTS OF RECURRENCE RISK OF PRE-ECLAMPSIA IN WOMEN WITH PREVIOUS PRE-ECLAMPSIA: A PROSPECTIVE STUDY
1L. C. Chappell, 1P. T. Seed, 2A. L. Briley, 1L. Poston, 1A. H. Shennan. 1King’s College London, London, UK, 2Guy’s and St Thomas’ NHS Foundation Trust, London, UK
Background: Factors determining recurrence risk for pre-eclampsia are sparse. The objective of our study was to elucidate demographic and clinical risk factors that affected risk of recurrent pre-eclampsia.
Methods: Indices of maternal and perinatal morbidity and mortality were determined in 541 women recruited into the Vitamins in Pre-eclampsia trial in 25 hospitals in the UK with previous pre-eclampsia, eclampsia or HELLP syndrome (hemolysis, elevated liver enzymes and low platelets) with data prospectively collected and rigorously validated. The main outcome measures were pre-eclampsia, delivery of small for gestational age infant and preterm delivery.
Results: The incidence of pre-eclampsia was 23% (n = 123) with 58% (n = 71) of these delivering preterm (<37 weeks’ gestation). Delivering an infant <10th customised birthweight centile complicated
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