FANTOMS
Fantoms
| The first 150 words of the full text of this article appear below. |
Oral medicinations commonly given to preterm newborns, such as iron, vitamins, mineral supplements and steroids, have usually been formulated for older patient groups. They may contain various additives (excipients) such as solvents, emulsifiers, preservatives, colourings, sweeteners and flavourings that have not been fully evaluated in terms of safe exposure in newborns. Whittaker and colleagues have estimated the exposure to these compounds during their hospital course of a group of preterm infants. Their findings are alarming and raise the possibility that they could even contribute to adverse outcome. For example, a preterm infant on furosemide may be exposed chronically to alcohol at a dose, weight for weight, equivalent to an adult consuming several units per week. The study highlights the need for better labeling of medicines and the importance of trials with appropriate outcome measures in establishing the balance of benefit and risks for the treatments used in the neonatal unit.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Relevant Articles
- Permissive hypotension in the extremely low birthweight infant with signs of good perfusion
- E M Dempsey, F Al Hazzani, and K J Barrington
Arch. Dis. Child. Fetal Neonatal Ed. 2009 94: F241-F244.[Abstract] [Full Text] [PDF]
- Extracting respiratory data from pulse oximeter plethysmogram traces in newborn infants
- D Wertheim, C Olden, E Savage, and P Seddon
Arch. Dis. Child. Fetal Neonatal Ed. 2009 94: F301-F303.[Abstract] [Full Text] [PDF]
- Toxic additives in medication for preterm infants
- A Whittaker, A E Currie, M A Turner, D J Field, H Mulla, and H C Pandya
Arch. Dis. Child. Fetal Neonatal Ed. 2009 94: F236-F240.[Abstract] [Full Text] [PDF]
- Treatment of asphyxiated newborns with moderate hypothermia in routine clinical practice: how cooling is managed in the UK outside a clinical trial
- D Azzopardi, B Strohm, A D Edwards, H Halliday, E Juszczak, M Levene, M Thoresen, A Whitelaw, P Brocklehurst on behalf of the Steering Group and TOBY Cooling Register participants
Arch. Dis. Child. Fetal Neonatal Ed. 2009 94: F260-F264.[Abstract] [Full Text] [PDF]
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
Services
- Email this link to a friend
- Similar articles in ADC Online
- Add article to my folders
- Download to citation manager
- Request Permissions
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
