PERSPECTIVES
SGA and SIDS: causality or association
Small for gestational age infants and sudden infant death syndrome: a confluence of complex conditions
Correspondence to:
Dr Carl E Hunt, 4550 North Park Avenue, Chevy Chase, Maryland 20815, USA; huntc@mail.nih.gov
Perspective on the paper by Malloy (see page 473)
| The first 150 words of the full text of this article appear below. |
"All illnesses have some hereditary contribution. Genetics loads the gun and environment pulls the trigger" (Francis Collins, Director, National Human Genome Research Institute, National Institutes of Health, 2006)
New data by Malloy1 further substantiate fetal growth restriction or being small for gestational age (SGA) as a risk factor for sudden infant death syndrome (SIDS). The similar odds ratios for sudden unexpected death in infancy (SUDI) excluding SIDS and for SIDS may reflect at least in part diagnostic shifts based on custom and preference of the medical examiner in classifying infant deaths consistent with SIDS not as SIDS but rather as, for example, "accidental suffocation" or "other ill-defined and unspecified causes". These new confirmatory data are important, but they provide no new insights regarding potential causal mechanisms for this association between SGA and SIDS. Does being SGA directly increase the risk for SIDS, or is
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- Size for gestational age at birth: impact on risk for sudden infant death and other causes of death, USA 2002
- Michael H Malloy
Arch. Dis. Child. Fetal Neonatal Ed. 2007 92: F473-F478.[Abstract] [Full Text] [PDF]
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