© 2005 Archives of Disease in Childhood Fetal and Neonatal Edition
LETTER
Hospital admissions for bronchiolitis in preterm infants in the absence of respiratory syncytial virus prophylaxis
Department of Paediatrics and Child Health, University College Cork, Ireland; pronabbala@doctors.org.uk
Keywords: bronchiolitis; hospital admissions; Palivzumab; premature infants; respiratory syncytial virus
| The first 150 words of the full text of this article appear below. |
Respiratory syncytial virus (RSV) is the causative agent in more than 50% of cases of bronchiolitis, with mycoplasma pneumonia, Para influenza 3, adenovirus, and some other viruses accounting for most of the remaining cases. Mortality from bronchiolitis ranges from 1% to 3%. Although as yet there is no safe and effective vaccine, passive immunity with Palivizumab has been shown to reduce hospital admissions of preterm babies, but no reduction in mortality, intensive care admissions, or ventilation days was observed.1 Critical appraisal of this study reveals that the number of infants to be treated to prevent one hospital admission is between 17 and 22.
The objectives of our study were to document local admission rates of premature infants from clinical bronchiolitis, assess local mortality and morbidity secondary to bronchiolitis, and examine seasonal and annual variation of bronchiolitis admissions. By examining hospital admission databases in Cork University Hospital, all admissions between 1997
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