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Amiodarone and breast feeding

¹ Pharmacy Department, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK; catherine.hall@trvi.nuth.northy.nhs.uk
² Neonatal Unit, Royal Victoria Infirmary

Keywords: amiodarone; breast feeding; supraventricular tachycardia

The first 150 words of the full text of this article appear below.

An infant was born at 33+2 weeks gestation by caesarean section after an in utero diagnosis of fetal ascites and tachycardia. The mother had received treatment during pregnancy with flecainide, amiodarone, and propranolol. The amiodarone was prescribed initially at 200 mg three times a day and was reduced to twice a day after 11 days.

The mother was keen to breast feed the baby. In previous reports of amiodarone and breast feeding, amiodarone treatment was for a maternal indication and hence continued post partum.^1,2 In this case, the amiodarone treatment stopped at delivery. However, because of the long terminal half life of amiodarone (about 50 days³), it could take several months for the level to fall. As one of the adverse effects of amiodarone is thyroid toxicity, the baby’s thyroid function was assessed and found to be normal. A decision was made to allow the mother to breast feed, . . . [Full text of this article]