Review
Hepatitis C in pregnancy
N Had
i
Department of Child
Health, King's College Hospital, Denmark Hill, London SE5 9RJ,
United Kingdom
Correspondence to: Dr Hadi
nedim.hadzic@kcl.ac.uk
Accepted 4 January
2001
| The first 150 words of the full text of this article appear below. |
 |
Introduction |
|---|
At the end of the second millennium, chronic hepatitis C virus
(HCV) infection is recognised as a major public health problem. The
global prevalence of chronic HCV infection is estimated to be
approaching 3% (over 170 million HCV infected people) with considerable geographical variation, ranging from 0.01-0.1% in the
United Kingdom and Scandinavia to 17-26% in Egypt.1 At present, the infection rate peaks among adults aged 30-49 and declines
sharply in those older than 50 years, suggesting acquisition of HCV
within the past 10-30 years.1 In the United States, the
estimated anti-HCV prevalence in 6-11 year old children is 0.2%, and
among adolescents aged 12-19 it is 0.4%.2 3 HCV induced
end stage chronic liver disease is a leading indication for
transplantation in the adult population of the United
States.1 2 Anti-HCV screening of blood products
introduced during the early 1990s has minimised this mode of HCV
acquisition, leaving vertical transmission from infected mothers
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Hutchinson, S J, Goldberg, D J, King, M, Cameron, S O, Shaw, L E, Brown, A, MacKenzie, J, Wilson, K, MacDonald, L
(2004). Hepatitis C virus among childbearing women in Scotland: prevalence, deprivation, and diagnosis. Gut
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