Fetal and Neonatal this issue
| The first 150 words of the full text of this article appear below. |
Large doses of oral vitamin A (5000 IU per day) failed to reduce the incidence of CLD when evaluated in a randomised controlled trial in Liverpool by Wardle et al (page 9). Previously, benefits have been claimed for high dose intramuscular vitamin A, and the Cochrane database reports a reduction in CLD from 62% to 55% after 5000 IU IM three times a week.
In this month's Archives, researchers in
Melbourne managed to persuade over 200 14 year olds to complete a
complex protocol of lung function tests (Doyle et
al. Arch Dis Child
2001;84:40-4). Eighty six had weighed less
than a kilo at birth in 1977, and many had been diagnosed with CLD in
infancy. Asthma was equally common in all the groups (about 20%).
There was no difference between the ex-premature group and the control
children, apart from the finding that those who
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