Archives of Disease in Childhood - Fetal and Neonatal Edition 2009;94:F193-F195
ORIGINAL ARTICLES
Retinopathy of prematurity in small-for-gestational age infants compared with those of appropriate size for gestational age
1 Centre for Reproductive Biology, Queens Medical Research Institute, Edinburgh, Scotland, UK
2 The Royal Hospital for Sick Children, Edinburgh, Scotland, UK
3 Princess Alexandra Eye Pavilion, Edinburgh, Scotland, UK
4 Wellcome Trust Clinical Research Facility, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, UK
5 Department of Child Life and Health, Edinburgh, Scotland, UK
Dr C A Dhaliwal, Room W1.12, Centre for Reproductive Biology, Queens Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, Scotland, UK; cdhaliwa{at}staffmail.ed.ac.uk
Aim: To compare the incidence of retinopathy of prematurity (ROP) in small-for-gestational age (SGA) infants compared with appropriate-for-gestational age (AGA) infants undergoing eye screening in the Lothian region of south east Scotland 1990–2004.
Methods: All infants in Lothian born with birth weight <1500 g and/or gestational age <32 weeks underwent eye screening by two experienced paediatric ophthalmologists. The presence of any stage of ROP (1–5), severe (stage 3 or greater) ROP and treated ROP was compared between the SGA and AGA infants using 
2 or Fisher exact tests. SGA was defined as birth weight below the 10th centile for gestational age.
Results: A total of 1413 babies with birth weights <1500 g and/or gestational age <32 weeks underwent eye screening; 329 (23%) were SGA. SGA infants born at gestational ages 26–31 weeks were more likely to develop any stage of ROP (p<0.01) than their AGA peers. SGA infants were also more likely to develop severe ROP (gestational age 26–27 weeks, p<0.01; 28–29 weeks, p = 0.01; 30–31 weeks, p = 0.01).
Conclusions: SGA infants who underwent eye screening in the Lothian region of south east Scotland from 1990 to 2004 were significantly more likely to develop ROP and more severe disease than AGA infants.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Relevant Article
- Fantoms
- Ben Stenson
Arch. Dis. Child. Fetal Neonatal Ed. 2009 94: F157.[Extract] [Full Text] [PDF]
eLetters:
Read all eLetters
- Small for gestational age infants are at risk of developing early severe ROP.
- Emma Heckford, et al.
- Fetal Neonatal Ed. Online, 2 Jul 2009 [Full text]
- Full Text
- Full Text (PDF)
-
All Versions of this Article:
adc.2008.143552v1
94/3/F193 most recent - Submit a response
- Read responses to this article
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
- Citation Map
Services
- Email this link to a friend
- Similar articles in ADC Online
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
