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Archives of Disease in Childhood - Fetal and Neonatal Edition 2006;91:F291-F292; doi:10.1136/adc.2005.078642
Copyright © 2006 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health

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SHORT REPORT

Determination of the prevalence of drug misuse by meconium analysis

S Williamson1, L Jackson2, C Skeoch2, G Azzim3, R Anderson3

1 Ninewells Hospital, Dundee, Scotland, UK
2 Princess Royal Maternity Hospital, Glasgow, Scotland, UK
3 University of Glasgow, Glasgow

Correspondence to:
Correspondence to:
Dr Williamson
University Department of Maternal and Child Health Sciences, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK; scott.williamson{at}tuht.scot.nhs.uk


ABSTRACT
In a pilot study to determine the local prevalence of maternal drug misuse, meconium from 400 infants was analysed for metabolites of eight controlled drugs. Cannabinoids were found in 13.25%, cocaine in 2.75%, and amphetamine in 1.75%. The prevalence of opiate and benzodiazepine misuse was masked by the presence of prescribed drugs so was undeterminable.


Keywords: meconium; maternal drug misuse; gas chromatography/mass spectrometry







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