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Freeze-thawing of breast milk does not prevent cytomegalovirus transmission to a preterm infant

¹ Children’s Hospital, University of Würzburg, Würzburg, Germany
² Institute of Medical Virology and Epidemiology of Viral Diseases, University Hospital of Tübingen, Tübingen, Germany
³ Institute of Virology and Immunobiology, University of Würzburg
⁴ Department of Medical Biometry, University Hospital of Tübingen

Correspondence to:
Correspondence to:
Dr Maschmann
Children’s Hospital, University of Würzburg, Josef-Schneider-Str 2, 97080 Würzburg, Germany; jens.maschmann{at}mail.uni-wuerzburg.de

ABSTRACT
Freezing human milk is recommended to inactivate cytomegalovirus (CMV). A case of a preterm infant exclusively receiving frozen breast milk from his CMV seropositive mother showed that storage of breast milk for two months at –20°C did not prevent symptomatic postnatal CMV infection.

Abbreviations: CMV, cytomegalovirus; BAL, bronchoalveolar lavage fluid; PCR, polymerase chain reaction

Keywords: breast milk; cytomegalovirus; infection; nutrition; preterm

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