REVIEW
Therapeutic hypothermia following perinatal asphyxia
Division of Clinical Sciences, Faculty of Medicine, Imperial College London, London, UK
Correspondence to:
Correspondence to:
A D Edwards
Imperial College London, Hammersmith Campus, Du Cane Rd, London, W12 ONN, UK; David.Edwards{at}imperial.ac.uk
Well constructed and carefully analysed trials of hypothermic neural rescue therapy for infants with neonatal encephalopathy have recently been reported. The data suggest that either selective head cooling or total body cooling reduces the combined chance of death or disability after birth asphyxia. However, as there are still unanswered questions about these treatments, many may still feel that further data are needed before health care policy can be changed to make cooling the standard of care for all babies with suspected birth asphyxia.
Abbreviations: aEEG, amplitude integrated EEG; GMF, gross motor function; ICE, Infant Cooling Evaluation; MRC, Medical Research Council; NICHD, National Institute of Child Health and Human Development; PDI, psychomotor developmental index
Keywords: brain cooling; hypothermia; neuroprotection
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Arch. Dis. Child. Fetal Neonatal Ed. 2006 91: F79.
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Bhat, M A
(2006). Re: Therapeutic hypothermia following perinatal asphyxia.. Arch. Dis. Child. Fetal Neonatal Ed.
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Ziino, A J A
(2006). Palliation bias is being overlooked in neonatal hypothermia trials.. Arch. Dis. Child. Fetal Neonatal Ed.
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[Full Text]
eLetters:
Read all eLetters
- Palliation bias is being overlooked in neonatal hypothermia trials
- Adrian J A Ziino
- Fetal Neonatal Ed. Online, 27 Feb 2006 [Full text]
- Re: Therapeutic hypothermia following perinatal asphyxia
- Mushtaq Ahmad Bhat, et al.
- Fetal Neonatal Ed. Online, 6 Mar 2006 [Full text]
- Author's Response: Re: Palliation bias is being overlooked in neonatal hypothermia trials
- A David Edwards, et al.
- Fetal Neonatal Ed. Online, 8 Mar 2006 [Full text]
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