© 2005 Archives of Disease in Childhood Fetal and Neonatal Edition
SHORT REPORT
Ibuprofen and cerebral oxygenation and circulation
1 Neonatal Intensive Care Unit, University Hospital Leuven, Herestraat 49 3000 Leuven, Belgium
2 Neonatal Intensive Care Unit, University Hospital Antwerp, Antwerp, Belgium
Correspondence to:
Correspondence to:
Dr Naulaers
Neonatal Intensive Care Unit, Department of Paediatrics, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium; gunnar.naulaers{at}uz.kuleuven.ac.be
The effect of prophylactic administration of ibuprofen on the cerebral circulation in preterm babies was measured with near infrared spectroscopy. No significant difference in the change in cerebral blood volume, change in cerebral blood flow, or tissue oxygenation index was found between administration of ibuprofen or placebo.
Abbreviations: CBV, cerebral blood volume; Hb, reduced haemoglobin; HbO2, oxyhaemoglobin; HbD, cerebral intravascular oxygenation (HbO2– Hb); HbT, total haemoglobin; TOI, tissue oxygenation index
Keywords: near-infrared spectroscopy; ibuprofen; tissue oxygenation index; cerebral blood flow
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Arch. Dis. Child. Fetal Neonatal Ed. 2005 90: F1.
This article has been cited by other articles:
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Aranda, J. V., Thomas, R.
(2005). Pharmacology Review: Intravenous Ibuprofen for Preterm Newborns. NeoReviews
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