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Archives of Disease in Childhood - Fetal and Neonatal Edition 2002;87:F75-F77; doi:10.1136/fn.87.2.F75
Copyright © 2002 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health.
Archives of Disease in Childhood Fetal and Neonatal Edition 2002;87:F75-F77
© 2002 Archives of Disease in Childhood Fetal and Neonatal Edition

REVIEW

Cytomegalovirus transmission from breast milk in premature babies: does it matter?

P Bryant1, C Morley3, S Garland4, N Curtis2

1 Paediatric Infectious Diseases Unit, Department of General Medicine; Department of Microbiology & Infectious Diseases, Royal Children’s Hospital, Flemington Road, Parkville, VIC 3052, Australia
2 Paediatric Infectious Diseases Unit, Department of General Medicine; Department of Microbiology & Infectious Diseases; Department of Paediatrics, University of Melbourne, Royal Children’s Hospital, Parkville, VIC 3052, Australia
3 Department of Neonatal Medicine, Royal Women’s & Children’s Hospitals, Carlton, VIC 3053, Australia
4 Department of Microbiology and Infectious Diseases, Royal Women’s & Children’s Hospitals, Carlton, VIC 3053, Australia

Correspondence to:
Correspondence to:
Dr Curtis, Department of Paediatrics, University of Melbourne, Royal Children’s Hospital, Flemington Road, Parkville, VIC 3052, Australia;
curtisn{at}cryptic.rch.unimelb.edu.au

ABSTRACT

There is evidence that CMV is commonly present in breast milk and is often transmitted to babies. CMV infection acquired postnatally can cause serious disease in very premature babies. Interventions to remove CMV from breast milk are possible but may damage other important constituents.

Keywords: cytomegalovirus; breast milk; prematurity

Abbreviations: CMV, cytomegalovirus; PCR, polymerase chain reaction


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  • Maschmann, J, Hamprecht, K, Weissbrich, B, Dietz, K, Jahn, G, Speer, C P (2006). Freeze-thawing of breast milk does not prevent cytomegalovirus transmission to a preterm infant.. Arch. Dis. Child. Fetal Neonatal Ed. 91: F288-F290 [Abstract] [Full Text]  
  • Curtis, N, Chau, L, Garland, S, Tabrizi, S, Alexander, R, Morley, C J (2005). Cytomegalovirus remains viable in naturally infected breast milk despite being frozen for 10 days. Arch. Dis. Child. Fetal Neonatal Ed. 90: F529-F530 [Abstract] [Full Text]  
  • Meier, J., Lienicke, U., Tschirch, E., Kruger, D. H., Wauer, R. R., Prosch, S. (2005). Human Cytomegalovirus Reactivation during Lactation and Mother-to-Child Transmission in Preterm Infants. J. Clin. Microbiol. 43: 1318-1324 [Abstract] [Full Text]  
  • Lindemann, P C, Foshaugen, I, Lindemann, R (2004). Characteristics of breast milk and serology of women donating breast milk to a milk bank. Arch. Dis. Child. Fetal Neonatal Ed. 89: F440-F441 [Abstract] [Full Text]  

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